ProntOral®: antimicrobial mouthwash — complete user guide

ProntOral® is one of the most modern antimicrobial mouthwashes on the global healthcare market — developed by the German B|Braun Melsungen , exclusively available in Greece through Traumacare .

In this guide we have gathered all the information you need to use it correctly — whether as a patient, a caregiver, or a healthcare professional.

What is ProntOral® in a sentence

ProntOral® is a colorless rinse-free mouthwash 250 ml , designed for antimicrobial cleaning and decolonization of the oral cavity and pharynx — chlorhexidine-free and alcohol-free .

Composition

Ingredient	Function
Polyhexanide (PHMB, 0.1-0.2%)	Antimicrobial activity against Gram+, Gram−, fungi and enveloped viruses
Surfactants	Mechanical cleaning, biofilm destabilization
Peppermint aroma	Fresh feeling, good tolerance
Pure water	Carrier

The solution does not contain alcohol, chlorhexidine, dyes, sucrose.

Official indications

According to the official B|Braun catalogue, ProntOral® is indicated for:

1. Decolonization of the oral cavity and pharynx by multidrug-resistant microbes (MRSA, VRE, ESBL)
2. Prevention of dental plaque formation
3. Prevention of caries
4. Supportive care of gingivitis and periodontitis
5. Inhibition of the growth, spread and transmission of multidrug-resistant microorganisms
6. Support mechanical cleaning of the oral cavity

In addition to the official indications, it is used clinically for:

• Treatment of aphthous ulcers (oral ulcers)
• Treatment of halitosis
• Supportive care in mucositis of chemo-/radiotherapy
• VAP prevention in the ICU
• Pre-surgical MDRO decolonization bundle together with Prontoderm® Set

How to use

Daily oral hygiene (adults)

• Dosage: 10 ml stand-alone solution
• Frequency: 1–2 times daily
• Rinse duration: 30 seconds
• When: After brushing and flossing
• Rinse with water: No rinse-free

Targeted use for canker sores or bad breath

• Frequency: 3–4 times daily
• Duration: Until symptoms resolve (usually 5–10 days)
• Topical on canker sores: Application with a cotton swab directly to the lesion

Pre-surgical MDRO decolonization

• Start: 5 days before surgery
• Frequency: 2–3 times daily
• Combination: With Prontoderm® Solution + Foam + Wipes + Nasal Gel (Prontoderm® Set)

Oral care ICU (intubated patient)

• Frequency: Every 4 hours (6 applications/day)
• Procedure: 10 ml via brush/sponge + suction (not swallowed)
• Duration: Throughout intubation

Chemotherapy mucositis

• Onset: 7 days before start of treatment
• Frequency: 4–6 times daily
• Duration: Throughout treatment + 2 weeks later

Elderly at home

• Frequency: 2 times a day
• Application: With a sponge/pen if the patient cannot rinse
• Note: Always in a semi-sitting position (45°)

Where used clinically

• Hospitals — ICU, surgical departments, oncology clinics, pathology
• Nursing homes — daily oral care
• Home care — by caregivers, after training
• Dental offices — after scaling, extraction, implant

For which ages is it suitable

• Children under 4 years: Contraindicated (risk of swallowing)
• Children 4–12 years: With a reduced dose of 5 ml and always under supervision
• Adolescents and adults: Full dosage of 10 ml
• Elderly: Full dosage of 10 ml, particularly suitable due to good tolerance

Contraindications and caution

• Known hypersensitivity to biguanides (rare)
• Pregnancy and lactation: Not without medical advice
• Children <4 years: Contraindicated

In these groups, consult a doctor or pharmacist before use.

Side effects

ProntOral® has an excellent safety profile. Rarely reported:

• Slight transient taste alteration (<5%)
• Dry mouth if used >6× daily

Unlike chlorhexidine, does not cause tooth staining, dysgeusia, or interaction with fluoride toothpaste.

Maintenance and storage

• Temperature: At room temperature (15–25°C), out of direct sunlight
• Shelf life sealed: 36 months
• Shelf life after opening: 8 weeks
• Children: Keep out of reach of children
• Note: Should not be swallowed in large quantities

How to tell it apart from common mouthwashes

Characteristic	ProntOral®	Common mouthwashes (alcohol-based)	Chlorhexidine
Alcohol	❌	✅ (10-26%)	Often ✅
Chlorhexidine	❌	❌	✅
Action against MDROs	✅	❌	✅
Tooth staining	❌	None	✅ Common
Dysgeusia	<5%	<5%	20-30%
Daily use	✅	✅	❌ only short-term
In children	✅ >4 years	Usually not	No

Where can I buy ProntOral® in Greece

Traumacare is the exclusive distributor of B|Braun in Greece. ProntOral® is available:

• Online: traumacare.gr/product/190-b-braun-prontoral with free delivery nationwide
• Hospital supply: Contact 2311 286262 for group orders
• Retail price (May 2026): €17.96 for 250 ml

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The entire ProntOral® Cluster

• #00 — ProntOral®: complete user guide
• #01 — Polyhexanide (PHMB) in oral decolonization
• #02 — Pre-surgical MDRO decolonization bundle
• #03 — VAP prevention in the ICU
• #04 — Mucositis in oncology patients
• #05 — ProntOral® in home care
• #06 — ProntOral® vs chlorhexidine
• #07 — From dental prophylaxis to hospital-acquired infection
• #08 — Dental plaque
• #09 — Cervical cancer
• #10 — Gingivitis
• #11 — Periodontitis
• #12 — Oral thrush
• #13 — ProntOral® vs Curasept
• #14 — ProntOral® vs Elgydium & Hexoral